Editor-in-Chief
Anastasis Stephanou
University College London
London UK

Featured Image

The murine myoblast cells differentiate into multinucleated myotubes upon withdrawal of serum or mitogens from myoblast cultures. During differentiation, the morphology of myoblasts change to elongate and express muscle specific proteins, MHC (myosin heavy chain). This picture shows MHC-expressing myotubes after 4 days incubation in low serum media. For more information, see Jang et al., in this issue.

Journal Topics

  • Transcription and regulation
  • Stem cell biology
  • Cell death, growth and development
  • Endocrinology and cellular metabolism
  • Cardiovascular biology, neuroscience biology
  • Infection and immunity, viral diseases
  • Cancer biology

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April/May/June 2013

Volume 2, Issue 2

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About the Featured Image
The murine myoblast cells differentiate into multinucleated myotubes upon withdrawal of serum or mitogens from myoblast cultures. During differentiation, the morphology of myoblasts change to elongate and express muscle specific proteins, MHC (myosin heavy chain). This picture shows MHC-expressing myotubes after 4 days incubation in low serum media. For more information, see Jang et al., in this issue.


Journal Description

JAK-STAT is now an Online-Only Journal

In January of 2012 we launched JAK-STAT, the first international peer-reviewed journal of its kind to focus exclusively on the JAK-STAT signaling pathway.

This is an excellent time to start this journal for several reasons:

  • Recent advances in JAK-STAT signaling have enhanced our understanding in signal transduction pathways.
  • JAK-STAT signaling are key events in controlling processes such as development, cell growth and homeostasis.
  • JAK-STAT pathways are altered in variety of diseases.
  • JAK-STAT will be a multi-disciplinary journal which will publish articles with translational relevance to therapy.

Recent Articles

In This Issue
JAK-STAT Volume 2, Issue 2 Table of Contents

Article
Review
Identification of STAT target genes in adipocytes

Article
Review
Targeting the tumor microenvironment: JAK-STAT3 signaling

Article
Review
JAK-STAT pathway and myogenic differentiation

Article
Review
Mechanisms of chronic JAK-STAT3-SOCS3 signaling in obesity

Article
Review
The tumor suppressor function of STAT1 in breast cancer

Article
Review
STAT3 and the Hyper-IgE syndrome: Clinical presentation, genetic origin, pathogenesis, novel findings and remaining uncertainties

Article
Review
Regulation of STATs by polycystin-1 and their role in polycystic kidney disease

Article
Review
JAK-STAT and feeding

Article
Commentary
CCL2 at the crossroad of cancer metastasis

Article
Commentary
Egr2 and Egr3 are the unique regulators for systemic autoimmunity

Article
Commentary
Why should we care about fly tumors?: The case of JAK-STAT and EGFR cooperation in oncogenesis

Article
Commentary
Making milk: A new link between STAT5 and Akt1

Article
Commentary
Mutual cytokine crosstalk between colon cancer cells and microenvironment initiates development of distant metastases

Article
Research Paper
Anti-STAT6 CTL activity in Stat6−/− mice: A cautionary tale

Article

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