Translation of mRNA into protein is a central step in the gene expression pathway. It is tightly controlled to provide cells with a rapid, robust and highly specific means to respond to changes in its microenvironment. Pathological regulation of translation occurs in many diseases including diabetes, heart failure and cancer. Agents to correct aberrant translation are being actively developed.
Translation is planned as a unique peer-reviewed, high-profile journal with a broad international audience. The launch of this journal reflects the tremendous progress in the field of translation over the past decade.
Translation will cover two major areas:
- Biochemistry and basic cell biology - structure, function and regulation of the translational apparatus in prokaryotic and eukaryotic cells;
- Translational control in biology and medicine - molecular and systems-level studies of translation across the entire spectrum of development and function of multicellular organisms and human health and disease.
We encourage reports of advances in cell free systems, in vitro, in vivo and in silico.
Translation welcomes submission of initial reports of novel agents that modulate translation, significant methodological advances and high quality descriptions of novel phenomena.
The journal will publish original research articles, brief reports, reviews, commentaries and meeting reports. All submissions will be rapidly screened for suitability by a member of the editorial board prior to peer-review, and only those meeting the highest standards of scientific merit will be accepted for publication.